Portrait of Magdalena Gładysz

Meet the team

Magdalena Gładysz

PhD Student

RUG

Alumni

I am working on Melt electrowriting (MEW) of scaffolds for replication of the blood-brain barrier (BBB) in dynamic on-chip cancer models.

Research

Projects

Melt electrowriting of human trabecular meshwork

Open-angle glaucoma is an eye condition where the trabecular meshwork (TM) loses its ability to properly maintain a healthy intraocular pressure (IOP) within the eye, as it is no longer able to evacuate aqueous humour from it. This results in a high IOP which damages the optic nerve and causes blindness. The exact mechanism behind […]

Novel Blood-Brain-Barrier in vitro models

We are working on Melt electrowriting (MEW) of scaffolds for recapitulation of the blood-brain barrier (BBB) in dynamic on-chip cancer models. This project aims to design a thin polymeric membrane on which relevant for BBB cells to form confluent layers with tight junctions. The membrane will serve as a minimalistic supporting scaffold, favoring cell-cell interactions […]

More Science than Fiction: growing spare parts ex vivo

Implanting biocompatible materials is nothing new, 3D printing of cells and extracellular matrix is well underway so growing replacement tissues in a lab is within reach. However, certain obstacles remain: How to culture functional tissues with robust and reproducible 3D architecture? Application of support structures can aid, but what if such scaffolds obstruct functionality of […]

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